@article{Sapon_2017, title={Treatment of anxiety-depressive disorders in patients with chronic pain}, volume={2}, url={https://e-medjournal.com/index.php/psp/article/view/31}, DOI={10.26766/pmgp.v2i2.31}, abstractNote={<p><strong>Background.</strong> The problem of the treatment of anxiety-depressive disorders in chronic pain is not solved, considering the significant somatization of psychopathological manifestations in dorsalgia and fibromyalgia; triggering and aggravating role of stress; lack of clear clinical recommendations for the management of patients with combined disease states.</p> <p><strong>Methods and materials.</strong> 164 patients with anxiety-depressive disorders and chronic pain were divided into the study group (n=81) with fibromyalgia and the comparison group (n=83) with joint pain (M25.5) or dorsalgia (M54 .0-9). Both groups were randomized into psychotherapeutic or pharmacotherapeutic treatment: F-Ph (fibromyalgia patients, psychopharmacotherapy - 42 persons), F-Ps (fibromyalgia patients, psychotherapy - 39 persons), JD-Ph (joint pain/dorsalgia patients, psychopharmacotherapy - 45 persons) JD-Ps (joint pain/dorsalgia patients, psychotherapy - 38 persons). <br> Psychopharmatherapy included SSRIs, SNRIs, and pregabalin in standard dosages according to the instructions. Psychotherapeutic interventions involved the following methods: psychoeducation, progressive muscle relaxation, rational therapy, art therapy, elements of cognitive behavioral therapy. Evaluating the effectiveness of the treatment was carried out at week 4 and 12 with Hamilton anxiety and depression scales (HAM-A and HAM-D).</p> <p><strong>Results.</strong> At week 4 of treatment, the most significant reduction in anxiety and depression symptoms occurred in psychopharmacotherapy groups, compared to psychotherapy. In particular, in patients with fibromyalgia (13.5 vs. 7.8, p=0.026 and 8.2 vs. 5.9, p=0.048, respectively).<br>At week 12 (end of treatment), there wasn’t noted any significant difference between the effectiveness of pharmacotherapy and psychotherapy interventions for reducing anxiety and depression symptoms.</p> <p><strong>Conclusion.</strong> These data indicate the similar effectiveness of pharmacotherapy and psychotherapy in the treatment of anxiety and depression symptoms in patients with chronic pain.</p>}, number={2}, journal={Psychosomatic Medicine and General Practice}, author={Sapon, Daria}, year={2017}, month={Jun.}, pages={e020231} }